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Our Research
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Making a difference. By testing your dog’s DNA with Wisdom Panel, you’re contributing to the largest veterinary genetic research study—ever. Each test brings us one step closer to the next scientific breakthrough in canine obesity, aging, or preventative care. In short, your results not only help you take better care of your pup but also empower us to improve the lives of the good-est boys and girls on earth for generations to come.
Intronic variant in POU1F1 associated with canine pituitary dwarfism
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A missense variant in IFT122 associated with a canine model of retinitis pigmentosa
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An across-breed validation study of 46 genetic markers in canine hip dysplasia
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Comprehensive genetic testing combined with citizen science reveals a recently characterized ancient MC1R mutation associated with partial recessive red phenotypes in dog
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Atypical Genotypes for Canine Agouti Signaling Protein Suggest Novel Chromosomal Rearrangement
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Variation in breeding practices and geographic isolation drive subpopulation differentiation, contributing to the loss of genetic diversity within dog breed lineages
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Recessive missense LAMP3 variant associated with defect in lamellar body biogenesis and fatal neonatal interstitial lung disease in dogs
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A putative silencer variant in a spontaneous canine model of retinitis pigmentosa
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Characterisation of canine KCNIP4: A novel gene for cerebellar ataxia identified by whole-genome sequencing two affected Norwegian Buhund dogs
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True Colors: Commercially-acquired morphological genotypes reveal hidden allele variation among dog breeds, informing both trait ancestry and breed potential
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TSEN54 missense variant in Standard Schnauzers with leukodystrophy
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NME5 frameshift variant in Alaskan Malamutes with primary ciliary dyskinesia
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Whole Genome Sequencing of Giant Schnauzer Dogs with Progressive Retinal Atrophy Establishes NECAP1 as a Novel Candidate Gene for Retinal Degeneration
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Canine models of human amelogenesis imperfecta: identification of novel recessive ENAM and ACP4 variants
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Heterozygosity testing and multiplex DNA panel screening as a potential tool to monitor health and inbreeding in a small, closed dog population.
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A novel KRT71 variant in curly‐coated dogs
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Origins and wanderings of the Finnish hunting spitzes
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Frequency and distribution of 152 genetic disease variants in over 100,000 mixed breed and purebred dogs.
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Frequency of five disease-causing genetic mutations in a large mixed-breed dog population (2011–2012)
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An intronic LINE-1 insertion in MERTK is strongly associated with retinopathy in Swedish Vallhund dogs
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Founder representation and effective population size in old versus young breeds-genetic diversity of Finnish and Nordic Spitz.
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Homozygous PPT1 Splice Donor Mutation in a Cane Corso Dog With Neuronal Ceroid Lipofuscinosis
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An Inversion DisruptingFAM134B Is Associated with Sensory Neuropathy in the Border Collie Dog Breed
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Genetic Panel Screening of Nearly 100 Mutations Reveals New Insights into the Breed Distribution of Risk Variants for Canine Hereditary Disorders
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A Novel Genome-Wide Association Study Approach Using Genotyping by Exome Sequencing Leads to the Identification of a Primary Open Angle Glaucoma Associated Inversion Disrupting ADAMTS17
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Two Independent Mutations in ADAMTS17 Are Associated with Primary Open Angle Glaucoma in the Basset Hound and Basset Fauve de Bretagne Breeds of Dog
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Genome Wide Analysis Indicates Genes for Basement Membrane and Cartilage Matrix Proteins as Candidates for Hip Dysplasia in Labrador Retrievers
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A web resource on DNA tests for canine and feline hereditary diseases
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Missense Mutation in CAPN1 Is Associated with Spinocerebellar Ataxia in the Parson Russell Terrier Dog Breed
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Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication
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Parallel Mapping and Simultaneous Sequencing Reveals Deletions in BCAN and FAM83H Associated with Discrete Inherited Disorders in a Domestic Dog Breed
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Complex population structure in African village dogs and its implications for inferring dog domestication history
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Genetic Mapping of Fixed Phenotypes: Disease Frequency as a Breed Characteristic
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Population Structure and Inbreeding From Pedigree Analysis of Purebred Dogs
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Single-Nucleotide-Polymorphism-Based Association Mapping of Dog Stereotypes
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