Our Scientific Legacy

Mars Veterinary has been conducting research in the field of canine genetics for nearly a decade starting with the initial canine genomics project in 1999. Today our technology powers two of the most comprehensive breed and genetic disease detection products in the market, the Banfield® Canine Genetic Analysis™ and the Royal Canin® Genetic Health Analysis™. Wisdom Panel, our at-home swab product features this same robust breed detection database and technology and a subset of disease testing as well.

All our products include detection for the largest breed count on the market—250+ breeds, types and varieties—and we hold the exclusive worldwide license for the genetic breed detection process as pioneered by Dr. Elaine Ostrander during her time at the Fred Hutchinson Cancer Research Institute. In addition Mars Veterinary holds the only commercial license in the United States for the MDR1 drug sensitivity screening from Washington State University.

As part of the largest pet care company in the world, we are able to draw on research from some of the most extensive databases of canine behavior, health and nutritional information to develop our tests. For nearly a decade starting with the funding of the initial canine genomics project, we have been passionate about advancing the science of canine genetics so we can help owners understand the unique needs of their dogs from the inside out contributing to genetic science and pulling from it, valuable insights into dogs as individuals. The more we know about our four-legged friends the better we can plan for their individual needs. Simply put…happier and healthier lives for our furry family members.

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MDR1 Technology Licensed From

Peer Reviewed Journal Articles

A single IGF1 allele is a major determinant of small size in dogs
Science. 2007 Apr 6;316(5821):112-5
Sutter NB, Bustamante CD, Chase K, Gray MM, Zhao K, Zhu L, Padhukasahasram B, Karlins E, Davis S, Jones PG, Quignon P, Johnson GS, Parker HG, Fretwell N, Mosher DS, Lawler DF, Satyaraj E, Nordborg M, Lark KG, Wayne RK, Ostrander EA

Population structure and inbreeding from pedigree analysis of purebred dogs
Genetics. 2008 May;179(1):593-601
Calboli FC, Sampson J, Fretwell N, Balding DJ

Single-nucleotide-polymorphism-based association mapping of dog stereotypes
Genetics. 2008 Jun;179(2):1033-44. Epub 2008 May 27
Jones P, Chase K, Martin A, Davern P, Ostrander EA, Lark KG

Genetic mapping of fixed phenotypes: disease frequency as a breed characteristic
2009 Jul-Aug;100 Suppl 1:S37-41. Epub 2009 Mar 25
Chase K, Jones P, Martin A, Ostrander EA, Lark KG. J Hered

Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication
Nature. 2010 Apr 8;464(7290):898-902. Epub 2010 Mar 17
Vonholdt BM, Pollinger JP, Lohmueller KE, Han E, Parker HG, Quignon P, Degenhardt JD, Boyko AR, Earl DA, Auton A, Reynolds A, Bryc K, Brisbin A, Knowles JC, Mosher DS, Spady TC, Elkahloun A, Geffen E, Pilot M, Jedrzejewski W, Greco C, Randi E, Bannasch D, Wilton A, Shearman J, Musiani M, Cargill M, Jones PG, Qian Z, Huang W, Ding ZL, Zhang YP, Bustamante CD, Ostrander EA, Novembre J, Wayne RK

A web resource on DNA tests for canine and feline hereditary diseases
Vet J. 2013 Aug;197(2):182-7. Epub 2013 Apr 11
Slutsky J, Raj K, Yuhnke S, Bell J, Fretwell N, Hedhammar A, Wade C, Giger U

Genome wide analysis indicates genes for basement membrane and cartilage matrix proteins as candidates for hip dysplasia in Labrador Retrievers
PLoS One. 2014 Jan 30;9(1):e87735. eCollection 2014
Lavrijsen IC, Leegwater PA, Martin AJ, Harris SJ, Tryfonidou MA, Heuven HC, Hazewinkel HA

Complex population structure in African village dogs and its implications for inferring dog domestication history
Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13903-8
Boyko AR, Boyko RH, Boyko CM, Parker HG, Castelhano M, Corey L, Degenhardt JD, Auton A, Hedimbi M, Kityo R, Ostrander EA, Schoenebeck J, Todhunter RJ, Jones P, Bustamante CD