Exercise-induced Collapse - EIC
Exercise-induced Collapse, or EIC is a genetic disorder that affects nerve and muscle it was first identified in Labrador Retrievers and has been found in many of the retrieving breeds and mixed-breed dogs with retriever ancestry. EIC is caused by a mutation in the DNM1 gene, and is usually first seen in dogs between five months and three years of age. Dogs who are affected may appear normal during low to moderate exercise, but as the name would suggest, develop weakness, wobbliness, and incoordination after strenuous exercise, particularly in the hind limbs. In severe cases, they may have short-term full body collapse and muscle weakness. These episodes typically last 5-10 minutes and most dogs will recover completely within 15-30 minutes.
Some of the factors that can contribute to EIC are a higher temperature or humidity that the dog is used to; extreme stress or excitement; and exercise that is continuous, intense and accompanied by a high level of excitement or anxiety. While the severity of EIC is mild to moderate for the majority of dogs and dogs are not painful during collapse or after recovery, affected dogs are generally unable to continue training or competition. They can live relatively normal lives if exercise and excitement are limited.